How do negative regulation and positive regulation in bacteria differ?
A) Only negative regulation involves promoters.
B) Only positive regulation involves promoters.
C) Only in negative regulation is transcription reduced when the regulatory complex binds to the promoter.
D) Only in positive regulation is transcription reduced when the regulatory complex binds to the promoter.
E) Positive regulation must occur at an earlier stage than negative regulation.

Question

Quizplus · Accepted Answer

In negative regulation, transcription is reduced (or inhibited) when the regulatory complex (such as a repressor) binds to the promoter or operator region, blocking RNA polymerase from binding and initiating transcription. In positive regulation, transcription is increased when the regulatory complex (such as an activator) binds to a regulatory DNA sequence (often upstream of the promoter) and enhances RNA polymerase binding and transcription initiation. Both negative and positive regulation can involve promoters and may occur at different stages of gene expression.

How Do Negative Regulation and Positive Regulation in Bacteria Differ