In eukaryotes, RNA polymerase by itself cannot bind to the chromosome and initiate transcription.It can bind and act only after regulatory proteins called _______ factors have been assembled on the chromosome.

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In eukaryotes, transcription factors are necessary for RNA polymerase to bind to DNA and initiate transcription. These factors help assemble the transcription machinery at the promoter region of genes.

In Eukaryotes, RNA Polymerase by Itself Cannot Bind to the Chromosome