Which statement about the toll-like receptors is true?

Question

Quizplus · Accepted Answer

Toll-like receptors are part of the innate immune system. They recognize conserved molecular patterns found in different pathogens and activate immune responses.

Answer: D
 Toll-like receptors initiate a signal transduction pathway that leads to the activation of transcription factors that control the expression of genes involved in the immune response. However, the response is limited to the cytoplasm, and there is no nuclear response.

Answer: E
 The signal transduction pathway triggered by Toll-like receptor binding leads to changes in the shape of NF-κB, which prevents it from entering the nucleus. This results in the downregulation of immune response genes.

Which Statement About the Toll-Like Receptors Is True