A body's tolerance to its own molecules involves

Question

Quizplus · Accepted Answer

The removal of immature B or T cells that show the potential to mount a response against self-antigens is called negative selection or central tolerance. This process eliminates potentially harmful self-reactive lymphocytes before they can mature and enter circulation. The presence of class II MHC molecules on all cells and CD4 on most cells are not directly related to the body's tolerance to its own molecules. Suppression of the cellular immune response and apoptosis of all cells with class I MHC self-antigens are also not accurate mechanisms for self-tolerance.

A Body's Tolerance to Its Own Molecules Involves