Which antibody class is most likely to trigger a large release of histamines?

Question

Quizplus · Accepted Answer

IgE antibodies are most likely to trigger a large release of histamines. This is because they are bound to mast cells and basophils, and when they encounter an antigen, they can cause these cells to degranulate and release histamines, which leads to an allergic response. IgG and IgM antibodies can also trigger histamine release, but to a lesser extent than IgE. IgL and monoclonal antibodies do not have the ability to trigger histamine release.

Which Antibody Class Is Most Likely to Trigger a Large