Which Statement Is True

Which statement is true?

A) Autoimmunity always results from a reaction to self antigens by the cellular, but not the humoral, immune system.
B) Failure of clonal deletion is a potential cause of autoimmunity.
C) Systemic lupus erythematosis is an immune deficiency disorder in which B cells lose the ability to give rise to plasma cells.
D) People with rheumatoid arthritis have an excess of a protein that blocks T cells from reacting to self antigens.
E) Type I diabetes is an autoimmune disease that results in cells losing their ability to respond to insulin.