A challenge to modern medicine is to design drugs that target the brain.Existing knowledge about the ability of _______ to cross the blood‒brain barrier seems to be the best starting point in the design of new treatments.

Question

Quizplus · Accepted Answer

Lipid-soluble substances are able to pass through the blood‒brain barrier and therefore are a good starting point for the design of drugs targeting the brain. This is because the barrier is made up of tightly packed cells that prevent most substances from entering the brain, but lipid-soluble substances are able to pass through because they are able to dissolve in the fatty cell membranes that make up the barrier.

A Challenge to Modern Medicine Is to Design Drugs That