The drug digitalis is used to treat patients with a weakened heart because it enhances cardiac contractility.Given what you know about ventricular muscle fibers and the ion channels involved in contraction, which of the following might represent the mechanism of action of digitalis?
A) It reduces Ca2+ in the sarcoplasm.
B) It slows the heartbeat.
C) It rapidly clears Ca2+ from the sarcoplasm.
D) It shortens the plateau phase of the action potential.
E) It increases the concentration of Ca2+ in the sarcoplasm and slows the reuptake of Ca2+ by the sarcoplasmic reticulum.
Correct Answer:
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