The Law of Bergonié and Tribondeau states that cells are most sensitive to radiation injury during mitosis (cell division).

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The Law of Bergonié and Tribondeau, formulated in 1906, states that cells are most sensitive to radiation injury during mitosis (cell division), specifically in the early stages of mitosis when the chromatin is condensed and the nuclear membrane disassembles. This is because the DNA is exposed and less able to repair radiation-induced damage.

The Law of Bergonié and Tribondeau States That Cells Are