The amyloid plaques and neurofibrillary tangles that are typical in Alzheimer's disease are also found in people with

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Down syndrome is a genetic disorder that is characterized by intellectual disability and is caused by the presence of an extra copy of chromosome 21. People with Down syndrome are at an increased risk of developing Alzheimer's disease later in life, and they often develop amyloid plaques and neurofibrillary tangles in their brain similar to those found in people with Alzheimer's disease.

The Amyloid Plaques and Neurofibrillary Tangles That Are Typical in Alzheimer's