When the same dose of a drug no longer produces the desired effect, it is said that the patient has developed

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Drug tolerance occurs when the body becomes accustomed to the effects of a drug, requiring higher doses to produce the same effect. This is a common phenomenon that occurs with long-term drug use, and can lead to addiction or dependence. An idiosyncratic reaction is an unexpected or unusual reaction to a drug that is not related to the dose or known pharmacological effects, while an allergic reaction is an immune response to a drug. A drug interaction occurs when two or more drugs interact with each other, causing a change in their effects. None of these choices specifically address the situation where the same dose of a drug no longer produces the desired effect.

When the Same Dose of a Drug No Longer Produces