LAAM is a synthetic opioid that has a longer duration than methadone.

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LAAM (Levo-alpha-acetylmethadol) is a synthetic opioid that has a longer duration than methadone. It has an elimination half-life of 2-3 days, compared to methadone's half-life of around 24 hours. Because LAAM has a longer duration of action, it can be taken less frequently than methadone, which can be beneficial for some individuals undergoing medication-assisted treatment for opioid use disorder. However, due to its potential for cardiac side effects, LAAM is not commonly prescribed in the United States.

LAAM Is a Synthetic Opioid That Has a Longer Duration