The most pronounced levels of tolerance to heroin can be observed in the degree of __________.

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Tolerance to heroin, a potent opioid, develops in various physiological and psychological aspects with repeated use. This includes tolerance to its pain-relieving effects (analgesia), the euphoric high it produces (euphoria), and its impact on slowing down breathing (respiratory depression). Over time, users need higher doses to achieve the same effects, indicating tolerance development in all these areas.

The Most Pronounced Levels of Tolerance to Heroin Can Be