Because of its low affinity for the NMDA receptor, this drug may only have an effect when the glutamate system is hyperactive and potentially neurotoxic.
A)galantamine
B)rivastigmine
C)donepezil
D)memantine

Question

Quizplus · Accepted Answer

Memantine is a low-affinity antagonist of the NMDA receptor, which means it only blocks the receptor when it is hyperactive and potentially causing neuronal damage. This makes it an effective treatment for neurodegenerative disorders such as Alzheimer's disease, where the glutamate system is believed to contribute to disease progression. Galantamine, rivastigmine, and donepezil are cholinesterase inhibitors and do not affect the NMDA receptor.

Because of Its Low Affinity for the NMDA Receptor, This