What Does the Fifth Amendment's Protection Against Self-Incrimination Mean

What does the Fifth Amendment's protection against self-incrimination mean?

A) That a person only has to be a witness against himself or herself is a felony is involved.
B) That a person does not have to be a witness against himself or herself if a first offense is involved.
C) That a person does not have to be a witness against himself or herself if prison time is involved as opposed to a mere fine.
D) That a person does not have to be a witness against himself or herself in a criminal case period.
E) That a person has to be a witness against himself or herself.