Antigen presentation refers to the process whereby fragments of

Question

Quizplus · Accepted Answer

Antigen presentation involves the display of fragments of self-proteins and pathogen proteins on HLA (human leukocyte antigen) molecules. HLA class I molecules present antigenic peptides derived from cytosolic proteins, while HLA class II molecules present peptides derived from extracellular proteins that are internalized and processed in endosomal compartments. Therefore, both classes of HLA molecules can display fragments of self-proteins and pathogen proteins. Option A is incorrect because pathogen proteins can be displayed on both HLA class I and II molecules. Option B is incorrect because while self-proteins can be displayed on HLA class II molecules, they can also be presented on HLA class I molecules.

Antigen Presentation Refers to the Process Whereby Fragments of