The most modified biome by human activity is the midlatitude grasslands.

Name: The most modified biome by human activity is the midlatitude grasslands.
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Midlatitude grasslands, also known as temperate grasslands, have been extensively modified by human activity, including agriculture, urbanization, and land-use changes. This has led to significant loss of native grassland species and fragmentation of habitats, as well as the introduction of non-native plant and animal species.

The Most Modified Biome by Human Activity Is the Midlatitude