The two most important symptoms of substance dependence are:

Question

Quizplus · Accepted Answer

Drug tolerance and withdrawal are the two most important symptoms of substance dependence. Tolerance refers to the need for increasing amounts of the substance to achieve the desired effect, while withdrawal refers to negative physical and psychological symptoms that occur when the substance is not taken. These two symptoms indicate a physical dependence on the substance and are essential criteria for diagnosing substance use disorders.

The Two Most Important Symptoms of Substance Dependence Are