Phineas Gage tragically had a tamping iron propelled through his head. Both left and right sides of the prefrontal cortex were severely damaged. As a result of the accident, Phineas Gage:

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Phineas Gage suffered a change in personality as a result of the damage to his prefrontal cortex. Prior to the accident, Gage was known to be conscientious and responsible, but after the accident, he became impulsive and irresponsible. This led to his difficulty in maintaining jobs and relationships.

Phineas Gage Tragically Had a Tamping Iron Propelled Through His