What New Idea Did Robert Boyle's Critique of Galen's Theory

What new idea did Robert Boyle's critique of Galen's theory introduce to the model of the material world?

A) Changes in matter were caused by tiny particles that behave in a regular,predictable fashion.
B) Invisible spirits and angelic influences were no longer needed to explain natural phenomena.
C) The human body was not governed by four humors,but was an incredibly complex and unpredictable system.
D) Direct observation of the human body through dissection was necessary in medical training.
E) The human body was seen as a constantly changing and evolving object rather than as a mere machine.