As a nurse, which of the following would you recognize as accurately describing the phenomenon of first-pass metabolism?
A) Sublingual medications pass first through the mucosal lining of the mouth.
B) Intradermal medications are absorbed first by the skin and then by underlying tissue.
C) Oral medications are metabolized by the liver before entering the bloodstream.
D) Intramuscular injections pass through the subcutaneous layer of skin into muscle.

Question

Quizplus · Accepted Answer

First-pass metabolism refers to the process in which oral medications are absorbed in the gastrointestinal tract and then metabolized by the liver before entering the systemic circulation. This can significantly impact the bioavailability and effectiveness of the medication.

As a Nurse, Which of the Following Would You Recognize