Cocaine and amphetamine both increase dopamine action. Cocaine specifically _______________ and amphetamine __________________.
A) blocks the dopamine transporter; stimulates the autoreceptor
B) stimulates the release of dopamine; stimulates the autoreceptor
C) blocks the dopamine transporter; stimulates the release of dopamine
D) stimulates the release of dopamine; blocks the dopamine transporter
E) stimulates the autoreceptor; blocks the dopamine transporter

Question

Quizplus · Accepted Answer

Cocaine blocks the dopamine transporter, preventing reuptake of dopamine and leaving more dopamine in the synaptic cleft. Amphetamine stimulates the release of dopamine from presynaptic neurons. Both actions increase dopamine concentration in the synaptic cleft.

Cocaine and Amphetamine Both Increase Dopamine Action