Which of the following is accurate regarding Alzheimer's disease?
A) Amyloid plaques and neurofibrillary tangles are unique to Alzheimer's disease.
B) Amyloid plaques are dying neurons that contain intracellular accumulations of tau protein.
C) Acetylcholinergic neurons in the basal forebrain are among the first cells to be affected in Alzheimer's disease.
D) Neurofibrillary tangles are extracellular deposits that consist of a dense core surrounded by degenerating axons and dendrites.
E) Dopaminergic neurons in the basal forebrain are among the first cells to be affected in Alzheimer's disease.

Question

Quizplus · Accepted Answer

Acetylcholinergic neurons in the basal forebrain are among the first cells to be affected in Alzheimer's disease. Amyloid plaques and neurofibrillary tangles are also characteristic of Alzheimer's disease, but they are not unique to it. Option B is incorrect because amyloid plaques are extracellular deposits, not dying neurons. Option D is incorrect because neurofibrillary tangles are intracellular deposits, not extracellular deposits. Option E is incorrect because dopaminergic neurons are not typically affected in Alzheimer's disease.

Which of the Following Is Accurate Regarding Alzheimer's Disease