Activation of a presynaptic autoreceptor on dendrites can produce a hyperpolarization that
A) releases more transmitter.
B) increases synthesis of transmitter.
C) increases reuptake of the transmitter.
D) reduces transmitter release by reducing the axon firing rate.
E) increases the number of receptors at the synapse.

Question

Quizplus · Accepted Answer

Activation of a presynaptic autoreceptor on dendrites can produce a hyperpolarization that reduces transmitter release by reducing the axon firing rate. This is called an inhibitory feedback loop or autoregulation.

Activation of a Presynaptic Autoreceptor on Dendrites Can Produce a Hyperpolarization