Reserpine blocks the storage of monoamines (dopamine, norepinephrine, serotonin) in vesicles, thus depleting their levels in the brain and producing a range of effects including sedation, depression, and Parkinsonism-like symptoms. It was previously used medically to treat high blood pressure, but it is no longer a first-line treatment due to its side effects.

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The Drug Reserpine

Question 81

Multiple Choice

The drug reserpine

A) was used medically to treat high blood pressure.
B) is used to treat myasthenia gravis.
C) blocks the storage of monoamines in vesicles.
D) can produce Parkinson's disease in some persons.
E) interferes with the synthesis of dopamine.

Correct Answer: