The nurse is caring for a client who has developed an infection that is resistant to fluoroquinolone therapy.The nurse knows that this resistance is due to which reasons?
Select all that apply.

Question

Quizplus · Accepted Answer

Fluoroquinolone resistance can occur due to mutations in DNA gyrase (A), which is a target for these antibiotics, the development of efflux pumps that expel the drug from the bacterial cell (B), and changes in the bacterial cell wall that make it impermeable to the drug (C). These mechanisms prevent the drug from effectively targeting and killing the bacteria.

The Nurse Is Caring for a Client Who Has Developed