A client with preexisting bipolar disorder is receiving filgrastim (Neupogen)for the management of neutropenia following chemotherapy treatments for lymphocytic leukemia.The oncology nurse recognizes that which preparation for bipolar disorder could complicate the management of the client's leukemia?

Question

Quizplus · Accepted Answer

Lithium carbonate may decrease the effectiveness of chemotherapy and radiation therapy, and there is a risk of leukemogenicity and hematological toxicity when given concurrently with filgrastim. Therefore, the use of lithium carbonate in a client with leukemia receiving filgrastim should be avoided or closely monitored by the oncology team. Clonazepam, valproic acid, and carbamazepine do not have any known significant interactions with filgrastim or leukemia treatment.

A Client with Preexisting Bipolar Disorder Is Receiving Filgrastim (Neupogen)for