The nurse is caring for a client taking both gemfibrozil (Lopid)and warfarin (Coumadin).To maintain safety relative to the interaction of these drugs,the nurse should monitor the client closely for which clinical manifestation?

Question

Quizplus · Accepted Answer

Gemfibrozil can increase the anticoagulant effects of warfarin, which may increase the risk of bleeding. Therefore, the nurse should monitor the client closely for any signs or symptoms of bleeding. Myolysis (A) is a potential adverse effect of gemfibrozil, but it is not related to the interaction with warfarin. Clot formation (B) is a concern when taking warfarin alone to prevent thromboembolic events, but it is not a typical manifestation of an interaction with gemfibrozil. Hyperlipidemia (D) is the condition that gemfibrozil is prescribed to treat, but it is not a manifestation of an adverse interaction with warfarin.

The Nurse Is Caring for a Client Taking Both Gemfibrozil