The Nurse Recognizes That Which Physiological Changes May Have What

The nurse recognizes that which physiological changes may have what effects on medication responses?
Select all that apply.

A) Decreased production of serum albumin may result in toxic levels of highly protein-bound drugs.
B) Declining efficiency of the blood-brain barrier may result in increased central nervous system symptoms.
C) Decreased contractility of the heart may result in decreased distribution of drugs.
D) Decreased gastric pH may result in decreased absorption.
E) Decreased body fat may result in decreased absorption of fat-soluble drugs.