The Nurse Is Teaching a Client the Importance of Taking

The nurse is teaching a client the importance of taking the medication as prescribed.Client teaching is guided by the nurse's knowledge of which principles of pharmacokinetics?
Select all that apply.

A) A medication taken by injection must cross the membranes of the gastrointestinal tract to get to the blood stream before it can be distributed throughout the body.
B) A drug may be exposed to several physiological processes while en route to target cells.
C) Liver enzymes may chemically change the drug.
D) Excretion organs such as kidneys and intestines must be healthy enough to eliminate the drug.
E) Many processes to which drugs are exposed are destructive,thereby helping facilitate the drug's movement throughout the body.