Bioavailability can be different between the generic and trade versions of a drug.When is it not appropriate for a generic drug to be substituted for a trade version?

Question

Quizplus · Accepted Answer

Generic substitution may not be appropriate for drugs with a narrow therapeutic index or critical care drugs, where minor differences in dose or bioavailability can have significant effects on the patient's health. Choices A, B, and C do not necessarily preclude generic substitution, as cost, onset of action, and inert ingredients can vary between different formulations of the same drug, whether generic or trade.

Bioavailability Can Be Different Between the Generic and Trade Versions