Which Statement Describes the Primary Difference Between Centrally Acting Muscle

Which statement describes the primary difference between centrally acting muscle relaxants and direct-acting antispasmodics?

A) Centrally acting agents inhibit neurons of the central nervous system,while direct-acting agents stimulate neurons of central nervous system.
B) Centrally acting agents stimulate neurons of the central nervous system,while direct-acting agents stimulate neurons of the peripheral nervous system.
C) Centrally acting agents inhibit neurons of the central nervous system,while direct-acting agents work at the level of the neuromuscular junction and skeletal muscles.
D) Centrally acting agents stimulate the central nervous system,while direct-acting agents inhibit neuronal conduction of the central nervous system.