When prescribing phosphodiesterase type 5 (PDE-5) inhibitors such as sildenafil (Viagra) patients should be screened for use of:

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Patients should be screened for use of nitrates when prescribing PDE-5 inhibitors such as sildenafil (Viagra) due to the risk of severe hypotension. Nitrates can be found in various medications used to treat angina and heart disease, such as nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Co-administration of nitrates and PDE-5 inhibitors can result in a dangerous drop in blood pressure.

When Prescribing Phosphodiesterase Type 5 (PDE-5) Inhibitors Such as Sildenafil