If a patient with H. pylori-positive peptic ulcer disease fails first-line therapy, the second-line treatment is:

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Second-line treatment for H. pylori-positive peptic ulcer disease often involves a combination therapy that includes a proton pump inhibitor (PPI) twice daily, metronidazole, tetracycline, and bismuth subsalicylate for 14 days. This regimen is recommended when first-line therapy fails, providing a different combination of antibiotics to overcome potential antibiotic resistance.

If a Patient with H