Patients with rheumatoid arthritis who are on chronic low-dose prednisone will need co-treatment with which medications to prevent further adverse effects?

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Patients with rheumatoid arthritis who are on chronic low-dose prednisone are at risk for developing osteoporosis and fractures due to the drug's effect on bone metabolism. Therefore, co-treatment with a bisphosphonate (such as alendronate or risedronate), calcium supplementation, and vitamin D is recommended to prevent further adverse effects. All of the above options are necessary for effective prevention of bone loss and fractures.

Patients with Rheumatoid Arthritis Who Are on Chronic Low-Dose Prednisone