Nonadherence Is Especially Common in Drugs That Treat Asymptomatic Conditions

Nonadherence is especially common in drugs that treat asymptomatic conditions, such as hypertension. One way to reduce the likelihood of nonadherence to these drugs is to prescribe a drug that:

A) Has a short half-life so that missing one dose has limited effect
B) Requires several dosage titrations so that missed doses can be replaced with lower doses to keep costs down
C) Has a tolerability profile with fewer of the adverse effects that are considered "irritating," such as nausea and dizziness
D) Must be taken no more than twice a day