Drugs that use CYP 3A4 isoenzymes for metabolism may:

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Drugs that use CYP 3A4 isoenzymes for metabolism may both induce the metabolism of another drug and inhibit the metabolism of another drug. This is because CYP 3A4 is involved in the metabolism of a large number of drugs, and when one drug is metabolized by this enzyme, it may affect the metabolism of other drugs that are also metabolized by CYP 3A4. Induction of CYP 3A4 can increase the metabolism of other drugs, leading to decreased effectiveness, while inhibition of CYP 3A4 can decrease the metabolism of other drugs, leading to increased toxicity.

Drugs That Use CYP 3A4 Isoenzymes for Metabolism May