Increasing the substrate concentration in an enzymatic reaction could overcome which of the following?

Question

Quizplus · Accepted Answer

Increasing substrate concentration can overcome competitive inhibition by allowing more substrate molecules to compete with inhibitor molecules for binding to the enzyme's active site. This increases the likelihood of substrate binding and therefore increases the rate of the reaction. However, increasing substrate concentration cannot overcome the need for a coenzyme, allosteric inhibition, or insufficient cofactors, as these factors affect the enzyme's activity in different ways that cannot be overcome simply by adding more substrate.

Increasing the Substrate Concentration in an Enzymatic Reaction Could Overcome