Spherocytosis is a human blood disorder associated with a defective cytoskeletal protein in the red blood cells (RBCs). What do you suspect is the consequence of such a defect?
A) abnormally shaped RBCs
B) an insufficient supply of ATP in the RBCs
C) an insufficient supply of oxygen-transporting proteins in the RBCs
D) adherence of RBCs to blood vessel walls, causing plaque formation

Question

Quizplus · Accepted Answer

A defective cytoskeletal protein in RBCs can cause them to become abnormally shaped, leading to spherocytosis. This condition results in premature destruction of RBCs by the spleen due to their inability to deform and pass through narrow capillaries. Symptoms include anemia, jaundice, and an enlarged spleen.

Spherocytosis Is a Human Blood Disorder Associated with a Defective