If you were developing artificial B-cell receptors (BCRs) based on the natural version and wanted to change the BCRs' ability to bind certain antigens, which region of the natural receptor would you alter?
A) transmembrane domain
B) the V and J regions of the light-chain and heavy-chain components of the BCR immunoglobulin
C) the C region of the light-chain and heavy-chain components of the BCR immunoglobulin
D) the region projecting into the cytosol of the cell

Question

Quizplus · Accepted Answer

The V and J regions of the light-chain and heavy-chain components of the BCR immunoglobulin are responsible for antigen binding. Therefore, altering these regions will change the BCRs' ability to bind certain antigens.

If You Were Developing Artificial B-Cell Receptors (BCRs) Based on the Natural