For the successful development of a vaccine to be used against a pathogen, it is necessary that ________.
A) the surface antigens of the pathogen stay the same
B) a rearrangement of the B-cell receptor antibodies takes place
C) all of the surface antigens on the pathogen be identified
D) the pathogen have only one epitope
E) the major histocompatibility (MHC) molecules are heterozygous

Question

Quizplus · Accepted Answer

The surface antigens of the pathogen must remain the same in order to develop a successful vaccine. This is because vaccines work by exposing the immune system to a harmless form of the pathogen, in order to train it to recognize and respond to the pathogen if it is encountered again in the future. If the surface antigens of the pathogen change, the immune system may not be able to recognize and respond to the pathogen effectively.

For the Successful Development of a Vaccine to Be Used