Which of the Following Best Describes the Neuroendocrine-To-Endocrine Pathway of Hormone

Which of the following best describes the neuroendocrine-to-endocrine pathway of hormone action?

A) A structure within the nervous system produces and release a hormone that regulate the activity of an endocrine gland.
B) A structure within the nervous system produces a hormone and releases it directly onto an endocrine gland.
C) A gland releases hormones directly into a neural structure, thus regulating neural functions.
D) A gland exhibits negative feedback on the nervous system by releasing hormones into neural tissue both directly and indirectly through the circulation.