Which of the following is TRUE during a typical cAMP-type signal transduction event?

Question

Quizplus · Accepted Answer

In a cAMP-type signal transduction event, the hormone binds to a receptor on the cell surface, which then activates adenylyl cyclase to produce cAMP (the second messenger). The cAMP then activates protein kinase A (PKA) through a conformational change. PKA then phosphorylates target proteins, resulting in a cellular response. Therefore, choice D is the correct option as adenylyl cyclase is activated after the hormone binds to the cell, but before protein phosphorylation occurs. Option A is incorrect as the second messenger is formed early in the signaling cascade and is necessary for the downstream events. Option B is also incorrect as the hormone does not directly bind to the second messenger, but to a receptor on the cell surface, which ultimately leads to the production of the second messenger. Option C is incorrect as the second messenger does not attract more hormones to the cell, but rather amplifies the signaling cascade by activating PKA, which then phosphorylates downstream proteins.

Which of the Following Is TRUE During a Typical CAMP-Type