The regulation of blood sugar levels and our stress responses are controlled in part by a negative feedback loop involving cortisol, adrenocorticotropic hormone (ACTH), and corticotropin-releasing hormone (CRH). What would likely be the result during times of stress if cortisol receptors in the hypothalamus were nonfunctional?

Question

Quizplus · Accepted Answer

When cortisol receptors in the hypothalamus are nonfunctional, the negative feedback loop that normally inhibits CRH production is disrupted. This leads to increased CRH and ACTH levels, stimulating more cortisol production. Cortisol raises blood sugar levels to provide energy during stress, so without regulation, blood sugar levels would rise to potentially dangerous levels.

The Regulation of Blood Sugar Levels and Our Stress Responses