In what way does hemoglobin act as a buffer against changes in blood pH?
A) Subsequent binding of oxygen is drastically reduced after the first one is bound.
B) Hemoglobin binds some of the excess protons released by carbonic acid.
C) Hemoglobin produces protons or hydroxide ions as needed to alter the blood pH.
D) Hemoglobin removes excess protons from the red blood cells so that they can be excreted through the kidneys.

Question

Quizplus · Accepted Answer

Hemoglobin binds some of the excess protons released by carbonic acid, therefore acting as a buffer against changes in blood pH. Carbonic acid, formed from carbon dioxide and water in the blood, dissociates into bicarbonate ions and protons. The bicarbonate ions are transported out of the red blood cell, and the protons can bind to the hemoglobin molecule, preventing a drastic drop in blood pH.

In What Way Does Hemoglobin Act as a Buffer Against