Cystic fibrosis is a genetic disorder in homozygous recessive (ff) humans that typically significantly reduces life expectancy. Over time, we would expect the f allele frequency to ________ for this trait.

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Cystic fibrosis is a recessive disorder, which means that individuals who carry only one copy of the gene (Ff) are asymptomatic carriers without experiencing the detrimental effects of the disease. Hence, such carriers can potentially pass on the faulty allele to their offspring. In populations where there is a high carrier frequency, there is an increased likelihood of two carriers having children, which increases the probability of homozygous recessive offspring. With time, this process leads to a steady increase in the incidence of the disorder, which ultimately results in a decrease in the frequency of the functional allele (F) in the gene pool. Thus, the most reasonable option is C - decrease.

Cystic Fibrosis Is a Genetic Disorder in Homozygous Recessive (Ff)