If you are a human geneticist looking for an ideal population in which to map disease genes, which of the following characteristics would help the mapping study?
A) small family sizes with well-known genealogies
B) a population where all members have the disease
C) large family sizes with little known genealogies
D) large family sizes with well-known genealogies

Question

Quizplus · Accepted Answer

Large family sizes with well-known genealogies would help in creating pedigrees and tracing the inheritance patterns of the disease gene within the family. This information can then be used to map the disease gene to a specific location on a chromosome. Small family sizes (A) may not provide enough individuals to create informative pedigrees, while a population where all members have the disease (B) would not allow for the identification of genetic factors that increase the risk of disease. Large family sizes with little known genealogies (C) may present challenges in accurately tracing inheritance patterns.

If You Are a Human Geneticist Looking for an Ideal