The drug cytochalasin B blocks the function of actin. Which of the following aspects of the cell cycle would be most disrupted by cytochalasin B?
A) spindle formation
B) spindle attachment to kinetochores
C) DNA synthesis
D) cell elongation during anaphase
E) cleavage furrow formation and cytokinesis

Question

Quizplus · Accepted Answer

Cytochalasin B inhibits actin function, which is involved in the formation of the contractile ring during cytokinesis. Therefore, cytochalasin B would most disrupt cleavage furrow formation and cytokinesis. The other aspects of the cell cycle listed (spindle formation, spindle attachment to kinetochores, DNA synthesis, and cell elongation during anaphase) are not primarily dependent on actin function.

The Drug Cytochalasin B Blocks the Function of Actin