A client, diagnosed with arthritis, should be instructed to avoid the use of NSAIDs because of which of the following prescribed medications?

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NSAIDs can interact with and decrease the effectiveness of Coumadin, increasing the risk of blood clots and other complications. Therefore, a client taking Coumadin should be advised to avoid NSAIDs, including aspirin, ibuprofen, and naproxen. Penicillin, digoxin, and diazide do not have significant interactions with NSAIDs.

A Client, Diagnosed with Arthritis, Should Be Instructed to Avoid