The use of natural analgesics, such as that derived from willow bark, dates back to 1898.

Name: The use of natural analgesics, such as that derived from willow bark, dates back to 1898.
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The use of natural analgesics, such as that derived from willow bark (which contains salicin, a precursor to aspirin), dates back to ancient civilizations, long before 1898. The synthesis of aspirin, a derivative of salicin, as we know it today, was achieved by Felix Hoffmann at Bayer in 1897.

The Use of Natural Analgesics, Such as That Derived from Willow